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Fragrance Allergy

Fragrance is found in far more products than perfume and cologne. It can be present in moisturizers, soaps, shampoos, cosmetics, deodorants, laundry products, household cleaners, and even products marketed as “natural.”

For people with a fragrance allergy, exposure to certain fragrance ingredients can cause allergic contact dermatitis, an itchy, red, eczema-type rash that may continue to return until the responsible products are identified and avoided.

At Vue Dermatology & Laser, we evaluate patients with persistent or recurring rashes and, when appropriate, use patch testing to help determine whether fragrance or another common allergen may be responsible.

Fragrance allergy is a type of allergic contact dermatitis. It occurs when the immune system becomes sensitized to a fragrance ingredient. After sensitization occurs, future skin contact with that ingredient can trigger inflammation.

Unlike an immediate allergic reaction, allergic contact dermatitis is delayed. The rash often does not develop until days after exposure.This delay is one reason fragrance allergy can be difficult to recognize. A moisturizer used in the morning, for example, may not produce noticeable symptoms until a couple of days later.

Fragrance ingredients are commonly added to products to give them a pleasant smell or mask the odor of other ingredients. Potential sources include:

  • Perfume and cologne
  • Moisturizers and creams
  • Soap and body wash
  • Shampoo and conditioner
  • Makeup and cosmetics
  • Deodorant
  • Sunscreen
  • Shaving products
  • Laundry detergent and fabric products
  • Household cleaning products
  • Candles and air fresheners

Because fragrance is so widespread, someone with a fragrance allergy may unknowingly encounter the same or related allergens in several different products.

Fragrance allergy can appear differently depending on where exposure occurs. Common symptoms include:

  • Itching
  • Redness
  • Dry or scaly skin
  • Swelling
  • Burning or irritation
  • Small bumps or blisters
  • Cracking or thickening of the skin with chronic exposure

The face, eyelids, neck, hands, and underarms are common locations.

Sometimes the location of the rash provides an important clue. A rash involving the neck, for example, might suggest exposure to perfume, hair products, or fragranced skincare products. However, the pattern is not always obvious.

Yes. This is one of the most confusing aspects of allergic contact dermatitis. Patients will often say, “I’ve used this lotion for ten years, so it can’t be causing my rash.” Unfortunately, that is not necessarily true.

Fragrance allergy develops after the immune system becomes sensitized to a particular ingredient. Sensitization can occur after repeated exposures, which means a product that caused no problems in the past can eventually trigger allergic contact dermatitis.

For this reason, long-term use of a product does not automatically rule it out as a possible cause.

These terms can be confusing, and they do not necessarily mean the same thing.

A fragrance-free product is generally formulated without ingredients added specifically to create or mask a scent. An unscented product may have little or no noticeable smell but can still contain fragrance ingredients used to mask the natural odor of other ingredients.

For patients with a known fragrance allergy, simply choosing something that does not smell strongly is therefore not enough. Ingredient labels, and the specific recommendations provided after patch testing, are much more useful.

“Natural” does not necessarily mean non-allergenic. Plant extracts and essential oils contain naturally occurring chemicals, some of which can cause allergic contact dermatitis in susceptible individuals. Products containing botanical or essential-oil ingredients may therefore still cause problems in someone with a fragrance allergy.

This is an important distinction because patients with sensitive skin sometimes switch from conventional products to heavily botanical or essential-oil-based products in an attempt to improve their rash. In some cases, this can actually make allergic contact dermatitis worse.

If your dermatologist suspects fragrance allergy, patch testing may be recommended. During patch testing, small amounts of common allergens are applied to the back using adhesive patches. The patches are removed after approximately 48 hours, and the skin is examined over several days for delayed allergic reactions.

Patch testing can include screening mixtures designed to identify many common fragrance allergies. Depending on your history and results, additional testing may sometimes be helpful. Importantly, patch testing is different from skin prick testing used to evaluate immediate allergies such as pollen or certain foods.

During an active flare, treatment may include prescription topical corticosteroids or other anti-inflammatory medications to reduce itching and inflammation. However, medication alone does not solve the underlying problem.

The most effective long-term treatment is avoiding the fragrance ingredients responsible for the reaction. Once an allergy has been identified, your dermatologist can help you understand where the allergen may be found and how to choose appropriate alternatives.

The skin may take several weeks to completely improve after the responsible products are discontinued, particularly if the dermatitis has been present for a long time.

Not necessarily. “Fragrance” represents a large and chemically diverse group of substances. Someone who reacts to one fragrance allergen may not react to every fragrance ingredient.

This is one reason individualized patch testing can be more useful than simply eliminating large categories of products indefinitely. Your dermatologist can help determine which allergens are relevant to your particular rash and how strict avoidance needs to be.

Consider a dermatologic evaluation if you have:

  • A rash that repeatedly affects the face, eyelids, neck, hands, or underarms
  • Eczema that continues despite treatment
  • A rash that seems related to skincare or personal care products
  • Symptoms that improve when you stop certain products and return when you restart them
  • Persistent dermatitis without an obvious cause

If allergic contact dermatitis is suspected, patch testing may help identify whether fragrance or another allergen is contributing to the problem.

Fragrance allergy can be frustrating because fragrance ingredients are found in so many everyday products. Simply treating the rash may provide temporary relief, but symptoms can return if exposure continues.

If you are experiencing a persistent or recurring rash and wonder whether your skincare or personal care products could be responsible, schedule an evaluation at Vue Dermatology & Laser.

References

  1. Johansen JD, Frosch PJ, Svedman C, et al. Hydroxyisohexyl 3-cyclohexene carboxaldehyde—known as Lyral: quantitative aspects and risk assessment of an important fragrance allergen. Contact Dermatitis.
  2. de Groot AC, Frosch PJ. Adverse reactions to fragrances: a clinical review. Contact Dermatitis. 1997;36(2):57-86.
  3. American Contact Dermatitis Society. Patient education and allergen information.
  4. American Academy of Dermatology. Contact dermatitis: diagnosis, treatment, and prevention.
At a Glance

Philip Eliades, MD, FAAD

  • Board-Certified Dermatologist
  • Served as Chief Resident at NewYork-Presbyterian Hospital/Weill Cornell Medical Center and Memorial Sloan Kettering Cancer Center
  • Author of numerous peer-reviewed research articles in leading Dermatology journals
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